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This gene encodes a transcription element that belongs to your homeobox gene family. Genes of the family members are very conserved amid vertebrates and essential for vertebrate embryonic progress. This gene has long been implicated in fetal pores and skin development and cutaneous regeneration.

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In mice, the same gene was proven to exhibit temporal and spatial colinearity in the main body axis of your embryo, but was not expressed inside the secondary axes, which implies features in entire body patterning along the axis. This gene and also other HOXB genes kind a gene cluster on chromosome 17 from the 17q21-22 region.[six]

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